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PEP -- Post-Exposure Prophylaxis

Time-sensitive HIV prevention after potential exposure

72-Hour PEP Window

Post-exposure prophylaxis (PEP) can prevent HIV if started within 72 hours of possible exposure. The sooner you start, the more effective it is.

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What is PEP?

PEP (Post-Exposure Prophylaxis) is a 28-day course of antiretroviral medication that can prevent HIV infection after potential exposure. It works by stopping the virus from establishing itself in your body.

PEP is not a morning-after pill -- it is a serious medical treatment. But it is highly effective when started early. You deserve to access it without shame or judgement.

Common reasons people seek PEP include condomless sex, condom breakage, sexual assault, or needle sharing. Whatever the reason, healthcare providers are there to help, not to judge.

The 72-Hour Window

Within 24 hours

Most effective. Start as soon as possible for the best protection.

24 -- 48 hours

Still effective. Do not delay further.

48 -- 72 hours

Less effective but still worth starting. Act now.

After 72 hours

The standard window has passed, but you should still speak with a healthcare provider. They may still be able to help.

How to Access PEP

PEP is available at:

  • Sexual health clinics (GUM clinics in the UK)
  • Emergency departments (A&E / ER) -- available 24/7
  • Some GP surgeries and walk-in centres
  • HIV/AIDS service organisations

PEP is free in most countries with public health systems. Even in countries without universal coverage, many clinics offer it at no cost or reduced cost. Do not let cost concerns stop you from seeking care.

What to Expect

You will take the medication once or twice daily for 28 days. Some people experience side effects like nausea or fatigue, but these usually improve after a few days. Your provider will schedule follow-up HIV tests at 4--6 weeks and 3 months.

You do not need to tell the healthcare provider every detail of what happened -- just that you may have been exposed to HIV and you need PEP. They are there to help.

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